30 Amantadine Off Label Uses
This review found that amantadine is fairly safe in children when used properly and offers a broad range of clinical utility with positive therapeutic effects in various conditions although its use in such conditions is strictly off label. The drug is renally cleared.
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Additionally there have been anecdotal reports that low dose amantadine has been successfully used to treat adhd.
Amantadine off label uses. This emedtv page discusses these and other amantadine uses in more detail including possible off label uses and its use in children. Increased dopamine can also help symptoms of adhd. Amantadine speeds recovery from severe traumatic brain injury.
Off label drug uses hospital pharmacy 711 literature review in a cochrane literature review performed to determine the safety and effi cacy of using amantadine in treating fatigue in patients with ms 5 randomized controlled trials published from 1987 to 2004 were included. Some info says used in tbi a few minuscule article say depression and moodhas a dopamine effect a few others say adhd. It is sometimes used off label to treat adhd symptoms in some patients.
Amantadine hydrochloride is indicated in the treatment of drug induced extrapyramidal reactions. Its actually an anti viral and commonly used in parkinsons treatment. Amantadine is used for treating the flu parkinsons disease and certain side effects due to other drugs.
It is thought to work by stimulating the production of dopamine. Amantadine has also been shown to relieve ssri induced sexual dysfunction. Although anticholinergic type side effects have been noted with amantadine when used in patients with drug induced extrapyramidal reactions there is a lower incidence of these side effects than that observed with the anticholinergic antiparkinson drugs.
Two of the studies assessed amantadine. Amantadine is frequently used to treat the characteristic fatigue often experienced by patients with multiple sclerosis. My psychiatrist prescribed it because ive got issues with adhd depression some executive functioning issues recal memory etc.
Amantadine is contraindicated in persons with end stage renal disease. A drug used to treat the symptoms of parkinsons disease also speeds recovery from severe traumatic brain injuries a new study has found. The researchers hypothesis for this trial then was that 4 weeks of treatment with amantadine given 4 to 16 weeks after injury in patients in vegetative and minimally conscious states after tbi would improve functional recovery and that the improvement would be maintained 2 weeks after drug washout.
Amantadine helps boost brain levels of dopamine a neurotransmitter linked to arousal. Amantadine is also used to alleviate symptoms of parkinsons disease such as tremors. Amantadine also seems to have moderate effects on multiple sclerosis ms related fatigue.
Off label uses fatigue in multiple sclerosis.
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